Introduction
The Catholic University of
Louvain, a renowned institution with a rich history of academic excellence, is
delighted to announce a promising opportunity for aspiring researchers in the
field of Placental Biology. We invite highly motivated and passionate
individuals to join our vibrant research community as Ph.D. students in this
exciting and cutting-edge area of study.
Overview of the Scholarship
Title: Ph.D. Student in Placental
Biology
Employer: Catholic University of
Louvain
Location: University Square 1,
Louvain-la-Neuve, Belgium
Published: 17th July 2023
Application
deadline: 3rd September 2023, 09:00 (Europe/Brussels) / 09:00 (CET)
Job
type: PhD
Field: Placental Biology, Animal
Science, Pharmacy & Pharmacology, Toxicology, Genetics, Molecular Biology,
Biomedicine, Bioinformatics
Project:
We are offering a Ph.D.
research opportunity focused on investigating the use of new HIF-2α inhibitors in the
treatment of severe placental dysfunction and its associated consequences, such
as fetal growth restriction and preeclampsia. Depending on the candidate's
background and preferences, the project may involve utilizing or developing
various methods, including:
- In vitro models based on cell culture: This includes the purification of primary trophoblast cells (using gradient, FACS, MACS methods), spheroids, organoids, and stem cells.
- Pharmacodynamic studies: Utilizing techniques like organ-on-chip, ex vivo placental perfusion, toxicity assessments, and LC-MS analysis.
- Molecular biology: Involving RT-qPCR, cloning, site-directed mutagenesis, transfection methods (siRNA, miRNA, adenovirus, CRISPR/Cas9), luciferase reporter assay, RNAseq, ChIPseq, and RNAscope.
- Protein analysis: Purification, assay, electrophoresis, ELISA, and western blotting techniques.
- Cellular and tissue imaging, 2D and 3D: Various imaging methods such as routine paraffin staining, phase contrast, live cell imaging (Nanolive), epifluorescence, confocal microscopy, immunostaining, 3D fluorescence imaging (Lightsheet), and contrast-enhanced tomography (nanoCT).
Profile:
We are looking for
candidates who meet the following criteria:
- Hold a master's degree in biomedical sciences, pharmaceutical sciences, medicine, engineering, or biology.
- Certified in 'Science and Medicine of Laboratory Animals' (FELASA B) or willing to acquire the certification.
- Experienced in utilizing in vitro, ex vivo, or in vivo models or an expert in one or several of the mentioned methods.
- Interest in placental biology, bioinformatics, or pharmacology.
- Possess a creative and motivated mindset with the ability to work independently within a new project.
- Demonstrate strong organizational skills and have a clear long-term vision of their research objectives.
- Proactive in problem-solving and capable of anticipating potential challenges.
- Proficient in both spoken and written English and French.
- Display versatility, autonomy, and the ability to collaborate effectively in a multicultural and multidisciplinary team environment, fostering a culture that values learning from both successes and failures.
Funding:
This is a full-time
employment opportunity with a contract initially open for 1 year, with the
possibility of extension. The candidate is encouraged to apply for additional
funding from external bodies such as FNRS, FRIA, FSR. The potential start date
for the position is as early as October 1, 2023.
Requirements:
Research Field: Medicine
(Medical Sciences), Pharmacological Sciences (Other), Biological Sciences
(Other)
Education Level: Master
Degree or equivalent
Languages: Excellent
proficiency in English and French
Years of Research
Experience: None required
To Apply:
Interested candidates should
contact Dr. Arthur Colson at arthur.colson@uclouvain.be and provide an academic
CV, a cover letter, reference letter(s), and a list of any publications.
To
apply for scholarship Click Here
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